Tg(Wap-cre)15Nki
Transgene Detail
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| Symbol: |
Tg(Wap-cre)15Nki |
| Name: |
transgene insertion 15, The Netherlands Cancer Institute |
| MGI ID: |
MGI:3801315 |
| Transgene: |
Tg(Wap-cre)15Nki Location: unknown
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| Alliance: |
Tg(Wap-cre)15Nki page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Wap-cre)15Nki expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Wap (MGI:98943) |
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Mutation details: The transgene consists of a 4.5 kb genomic fragment of the mouse whey acidic protein promoter (Wap) followed by a rabbit beta-globin intron, cre coding sequence, and a transcription termination/polyadenylation fragment from the human growth hormone gene. The purified 7.8 kb fragment was microinjected into one-cell stage embryos from FVB/N mice. This is a low expressing line (15).
(J:171765)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Wap
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:171765 Derksen PW, et al., Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice. Dis Model Mech. 2011 May-Jun;4(3):347-58 |
| All: |
2 reference(s) |
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Analysis Tools
