Wt1<tm1(EGFP/cre)Wtp> Targeted Allele Detail MGI Mouse (MGI:3801681)

Wt1^{tm1(EGFP/cre)Wtp}
Targeted Allele Detail

Summary

Symbol:	Wt1^{tm1(EGFP/cre)Wtp}
Name:	WT1 transcription factor; targeted mutation 1, William T Pu
MGI ID:	MGI:3801681
Synonyms:	Wt1^GFPCre
Gene:	Wt1 Location: Chr2:104956874-105003959 bp, + strand Genetic Position: Chr2, 55.06 cM, cytoband E
Alliance:	Wt1^{tm1(EGFP/cre)Wtp} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:137426
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Mutation
description

Allele Type:

Targeted (Recombinase)

Mutations:

Insertion, Intragenic deletion

Wt1^{tm1(EGFP/cre)Wtp} expression driven by 1 gene

Mutation details: Exon 1 was replaced with an EGFP-cre derived from pBS592 and an frt-flanked neo cassette. Germ line, flp-mediated recombination was used to remove the neo cassette. (J:137426)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wt1 (mouse) Summary of all recombinase alleles driven by Wt1. Comparative matrix view of recombinase activities Alliance mouse Wt1 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

52027 assay results
2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Wt1 Mutation:	34 strains or lines available

References

Original:	J:137426 Zhou B, et al., Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature. 2008 Jul 3;454(7200):109-13
All:	49 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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