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Tg(Lck-betarec)1Abnd
Transgene Detail
Summary
Symbol: Tg(Lck-betarec)1Abnd
Name: transgene insertion 1, Antonio Bernad
MGI ID: MGI:3802615
Synonyms: Lck-beta, Tgbeta1
Transgene: Tg(Lck-betarec)1Abnd  Location: unknown  
Alliance: Tg(Lck-betarec)1Abnd page
Transgene
origin
Strain of Origin:  C57BL/6 x CBA/J
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Lck-betarec)1Abnd expression driven by 1 gene
 
Mutation detailsThe Lck promoter was used to drive immature T cell-specific expression of the prokaryotic beta-recombinase gene. Five lines where created, two with high levels of expression in the thymus (lines 1 and 2). Line 1 contains 15 transgene insertions whereas line 2 contains three. Expression levels were high in the thymus, lower in spleen and lymph nodes, and absent in liver and brain. (J:137580)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lck (species not specified)
Summary of all recombinase alleles driven by Lck.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:137580 Servert P, et al., In vivo site-specific recombination using the beta-rec/six system. Biotechniques. 2008 Jul;45(1):69-78
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory