Tg(Myh6-cre/PGR*)1Mds
Transgene Detail
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| Symbol: |
Tg(Myh6-cre/PGR*)1Mds |
| Name: |
transgene insertion 1, Michael D Schneider |
| MGI ID: |
MGI:3803295 |
| Synonyms: |
alphaMHC-CrePR1, line 6299, MHC-Cre |
| Transgene: |
Tg(Myh6-cre/PGR*)1Mds Location: unknown
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| Alliance: |
Tg(Myh6-cre/PGR*)1Mds page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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mifepristone |
| Mutation: |
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Insertion
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Tg(Myh6-cre/PGR*)1Mds expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Myh6 |
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Mutation details: The Myh6 promoter was used to drive cardiac myocyte-specific expression of an inducible cre fused to the mutated ligand-binding domain of human PGR (amino acids 641-891). Three founder lines, 6306, 6297, and 6299, were generated with line 6306 showing the lowest level of cre protein by Western blot and lowest prevalence of ligand-dependent recombination, with 6299 showing the highest level of recombination. Copy number was found to be highest in 6299 (about 10) with 6306 having the lowest (1).
(J:127215)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Myh6
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:127215 Minamino T, et al., Inducible gene targeting in postnatal myocardium by cardiac-specific expression of a hormone-activated Cre fusion protein. Circ Res. 2001 Mar 30;88(6):587-92 |
| All: |
7 reference(s) |
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Analysis Tools
