Del(10Prtn3-Elane)1Deje
Targeted Allele Detail
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| Symbol: |
Del(10Prtn3-Elane)1Deje |
| Name: |
Deletion, Chr 10, Dieter E Jenne 1 |
| MGI ID: |
MGI:3803339 |
| Synonyms: |
Del1Deje, Ela2/Prtn3tm1Deje, Elane/Prtn3tm1Deje, Prtn3-Ela2- |
| Gene: |
Del(10Prtn3-Elane)1Deje Location: unknown Genetic Position: Chr10, Syntenic
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intergenic deletion, Intragenic deletion
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Del(10Prtn3-Elane)1Deje involves 2 genes/genome features (Prtn3, Elane)
View all
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Mutation details: Exons 2 through 5 of Prtn3 and exons 1 through 3 of Elane were replaced with a floxed neo cassette. The neo cassette was removed by transient expression of cre in ES cells. The absence of transcript from either gene was confirmed by RT-PCR on bone marrow extracts.
(J:137674)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Del(10Prtn3-Elane)1Deje Mutation: |
0 strains or lines available
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| Original: |
J:137674 Kessenbrock K, et al., Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin. J Clin Invest. 2008 Jul;118(7):2438-47 |
| All: |
8 reference(s) |
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Analysis Tools
