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Tg(KRT5-cre/ERT2)AJdg
Transgene Detail
Summary
Symbol: Tg(KRT5-cre/ERT2)AJdg
Name: transgene insertion A, John DiGiovanni
MGI ID: MGI:3807716
Transgene: Tg(KRT5-cre/ERT2)AJdg  Location: unknown  
Alliance: Tg(KRT5-cre/ERT2)AJdg page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(KRT5-cre/ERT2)AJdg expression driven by 1 gene
 
Mutation detailsA DNA construct composed cre sequence and the human tamoxifen responsive estrogen receptor ligand-binding domain (ERT2 was placed under the control of the bovine KRT5 promoter. Three founder lines were produced. Line A showed the highest inducible cre expression. (J:138529)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT5 (cattle)
Summary of all recombinase alleles driven by KRT5.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:138529 Kataoka K, et al., Stage-specific disruption of Stat3 demonstrates a direct requirement during both the initiation and promotion stages of mouse skin tumorigenesis. Carcinogenesis. 2008 Jun;29(6):1108-14
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory