Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Sox1tm1(cre)Take
Name:	SRY (sex determining region Y)-box 1; targeted mutation 1, Takumi Era
MGI ID:	MGI:3807952
Synonyms:	Sox1-Cre
Gene:	Sox1  Location: Chr8:12445519-12449555 bp, + strand  Genetic Position: Chr8, 5.73 cM, cytoband A1-A2
Alliance:	Sox1tm1(cre)Take page

Germline Transmission:	Earliest citation of germline transmission: J:138918
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Sox1tm1(cre)Take expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sox1 (MGI:98357)   Mutation details: Cre recombines cDNA was inserted into the ATG codon start site of Sox1 by in-frame. PGK-NEO cassette was removed by transient Flp recombinase expression. (J:138918)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox1 (mouse) Summary of all recombinase alleles driven by Sox1. Comparative matrix view of recombinase activities Alliance mouse Sox1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

54 assay results 7 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox1 Mutation:	13 strains or lines available

Original:	J:138918 Takashima Y, et al., Neuroepithelial cells supply an initial transient wave of MSC differentiation. Cell. 2007 Jun 29;129(7):1377-88
All:	34 reference(s)