Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Gt(ROSA)26Sortm9(CAG-tdTomato)Hze
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 9, Hongkui Zeng
MGI ID:	MGI:3809523
Synonyms:	Ai9, Ai9(RCL-tdT, R26LSL-tdTomato, Rosa26Tomato, Rosa-CAG-LSL-tdTomato-WPRE, Rosa-LSL-TdTomato, ROSA:lxp-stp-lxp:tdTomato, Rs-tdTomato-R
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm9(CAG-tdTomato)Hze page

Germline Transmission:	Earliest citation of germline transmission: J:155793
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Conditional ready, Reporter) Mutation:    Insertion   Mutation details: The Rosa-CAG-LSL-tdTomato-WPRE targeting vector was designed with (from 5' to 3') a CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (CAG), an FRT site, a loxP-flanked STOP cassette (with stop codons in all 3 reading frames and a triple polyA signal), tdTomato sequence (a non-oligomerizing DsRed fluorescent protein variant with a 12 residue linker fusing two copies of the protein (tandem dimer)), a woodchuck hepatitis virus post-transcriptional regulatory element (WPRE; to enhance the mRNA transcript stability), a polyA signal, and an attB/attP-flanked PGK-FRT-Neo-polyA cassette. This entire construct was inserted between exons 1 and 2 of the Gt(ROSA)26Sor locus. (J:155793)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

522 assay results 38 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Gt(ROSA)26Sortm9(CAG-tdTomato)Hze

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	993 strains or lines available

Original:	J:155793 Madisen L, et al., A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci. 2010 Jan;13(1):133-40
All:	2389 reference(s)