Il17rbtm1Bud
Targeted Allele Detail
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| Symbol: |
Il17rbtm1Bud |
| Name: |
interleukin 17 receptor B; targeted mutation 1, Alison L Budelsky |
| MGI ID: |
MGI:3809835 |
| Synonyms: |
IL-17RB |
| Gene: |
Il17rb Location: Chr14:29718125-29730853 bp, - strand Genetic Position: Chr14, 18.39 cM
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| Alliance: |
Il17rbtm1Bud page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:139080
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A targeting vector was constructed to replace the region of exon 3 that encodes amino acids 38 through 73 with a neomycin selection cassette. Correct targeting was confirmed by Southern blotting. Cultured splenocytes failed to produce IL-5 or IL-13 when incubated with the ligand to the gene product.
(J:139080)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Il17rb Mutation: |
42 strains or lines available
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| Original: |
J:139080 Rickel EA, et al., Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J Immunol. 2008 Sep 15;181(6):4299-310 |
| All: |
12 reference(s) |
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Analysis Tools
