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Nectin1tm1Mjd
Targeted Allele Detail
Summary
Symbol: Nectin1tm1Mjd
Name: nectin cell adhesion molecule 1; targeted mutation 1, Michael J Dixon
MGI ID: MGI:3814719
Gene: Nectin1  Location: Chr9:43655251-43718758 bp, + strand  Genetic Position: Chr9, 24.42 cM, cytoband B
Alliance: Nectin1tm1Mjd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:140568
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 1 was replace with a neo cassette. The absence of protein was confirmd by western blot analysis on embryo tissue extracts. (J:140568)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nectin1 Mutation:  23 strains or lines available
References
Original:  J:140568 Barron MJ, et al., The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice. Hum Mol Genet. 2008 Nov 15;17(22):3509-20
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory