About   Help   FAQ
Batf3tm1Kmm
Targeted Allele Detail
Summary
Symbol: Batf3tm1Kmm
Name: basic leucine zipper transcription factor, ATF-like 3; targeted mutation 1, Kenneth M Murphy
MGI ID: MGI:3817232
Gene: Batf3  Location: Chr1:190830611-190841140 bp, + strand  Genetic Position: Chr1, 96.28 cM, cytoband H6
Alliance: Batf3tm1Kmm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:141064
Parent Cell Line:  MC50 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exons 1-2 were replaced by a floxed neomycin cassette. Cre-mediated recombination removed the neo cassette. Gene inactivation was confirmed by a lack of protein detected by immunoblot analysis of Th1 CD4+ T cells. (J:141064)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Batf3 Mutation:  18 strains or lines available
References
Original:  J:141064 Hildner K, et al., Batf3 deficiency reveals a critical role for CD8alpha+ dendritic cells in cytotoxic T cell immunity. Science. 2008 Nov 14;322(5904):1097-100
All:  249 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory