Summary | Transgene origin | Transgene description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Tg(Ins-Igf2)1Fbos
Name:	transgene insertion 1, Fatima Bosch
MGI ID:	MGI:3818739
Synonyms:	RIPI/IGF-II
Transgene:	Tg(Ins-Igf2)1Fbos  Location: unknown
Alliance:	Tg(Ins-Igf2)1Fbos page

Strain of Origin:

C57BL/6 x SJL

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Ins-Igf2)1Fbos expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Igf2 (MGI:96434)   Mutation details: The rat promoter was used to drive islet-specific expression of the mouse gene. Three lines were created (lines 1, 2 and 3) with similar phenotype. Line 1 was chosen as the representative line and has 40 copies of the transgene. (J:141527)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:141527 Devedjian JC, et al., Transgenic mice overexpressing insulin-like growth factor-II in beta cells develop type 2 diabetes. J Clin Invest. 2000 Mar;105(6):731-40
All:	11 reference(s)