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Nfe2l1tm1Mym
Targeted Allele Detail
Summary
Symbol: Nfe2l1tm1Mym
Name: nuclear factor, erythroid derived 2,-like 1; targeted mutation 1, Masayuki Yamamoto
MGI ID: MGI:3828165
Synonyms: Nrf1flox
Gene: Nfe2l1  Location: Chr11:96708240-96720794 bp, - strand  Genetic Position: Chr11, 60.12 cM, cytoband D-E
Alliance: Nfe2l1tm1Mym page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:143468
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A loxP site was inserted upstream of exon 4 and a floxed neo cassette followed by an IRES-EGFP replaces the non-coding portion of exon 4. (J:143468)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfe2l1 Mutation:  42 strains or lines available
References
Original:  J:143468 Ohtsuji M, et al., Nrf1 and Nrf2 play distinct roles in activation of antioxidant response element-dependent genes. J Biol Chem. 2008 Nov 28;283(48):33554-62
All:  10 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory