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Adarb1tm1Eme
Targeted Allele Detail
Summary
Symbol: Adarb1tm1Eme
Name: adenosine deaminase, RNA-specific, B1; targeted mutation 1, Ronald Emeson
MGI ID: MGI:3830728
Gene: Adarb1  Location: Chr10:77126560-77254104 bp, - strand  Genetic Position: Chr10, 39.72 cM, cytoband C
Alliance: Adarb1tm1Eme page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:144148
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream and a floxed PGK-neo cassette was inserted downstream of the editing site complementary sequence (ECS) region via homologous recombination. (J:144148)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adarb1 Mutation:  37 strains or lines available
References
Original:  J:144148 Feng Y, et al., Altered RNA editing in mice lacking ADAR2 autoregulation. Mol Cell Biol. 2006 Jan;26(2):480-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory