Olig3tm2(cre/ERT2)Cbm
Targeted Allele Detail
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| Symbol: |
Olig3tm2(cre/ERT2)Cbm |
| Name: |
oligodendrocyte transcription factor 3; targeted mutation 2, Carmen Birchmeier |
| MGI ID: |
MGI:3833733 |
| Synonyms: |
Olig3CreERT2 |
| Gene: |
Olig3 Location: Chr10:19232287-19234352 bp, + strand Genetic Position: Chr10, 8.33 cM
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| Alliance: |
Olig3tm2(cre/ERT2)Cbm page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:143526
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutations: |
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Insertion, Intragenic deletion
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Olig3tm2(cre/ERT2)Cbm expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: A cre/ERT2 along with an Frt flanked neomycin selection cassette, replaces Olig3 coding sequence and was fused in frame with the ATG codon of Olig3. Mutant mice were later crossed with Gt(ROSA)26Sortm1(FLP1)Dym mice to excise the neomycin selection cassette. This is a null allele.
(J:143526)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Olig3
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Olig3 Mutation: |
9 strains or lines available
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| Original: |
J:143526 Storm R, et al., The bHLH transcription factor Olig3 marks the dorsal neuroepithelium of the hindbrain and is essential for the development of brainstem nuclei. Development. 2009 Jan;136(2):295-305 |
| All: |
7 reference(s) |
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Analysis Tools
