Tg(Slc6a3-cre/ERT2)1Span Transgene Detail MGI Mouse (MGI:3835856)

Tg(Slc6a3-cre/ERT2)1Span
Transgene Detail

Summary

Symbol:	Tg(Slc6a3-cre/ERT2)1Span
Name:	transgene insertion 1, Rainer Spanagel
MGI ID:	MGI:3835856
Synonyms:	DATCreERT2, Tg(Slc6a3-ERT2)1Span
Transgene:	Tg(Slc6a3-cre/ERT2)1Span Location: unknown
Alliance:	Tg(Slc6a3-cre/ERT2)1Span page

Transgene
origin

Strain of Origin:

Not Specified

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(Slc6a3-cre/ERT2)1Span expression driven by 1 gene

Mutation details: A cassette encoding a tamoxifen-inducible form of cre recombinase was knocked into the ATG start site of a murine Slc6a3 gene located on BAC RP24-243J21. The transgene was expressed in dopaminergic neurons in the brain. (J:139693)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a3 (mouse) Summary of all recombinase alleles driven by Slc6a3. Comparative matrix view of recombinase activities Alliance mouse Slc6a3 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:139693 Engblom D, et al., Glutamate receptors on dopamine neurons control the persistence of cocaine seeking. Neuron. 2008 Aug 14;59(3):497-508
All:	26 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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