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Tg(Chat-cre)GM24Gsat
Transgene Detail
Summary
Symbol: Tg(Chat-cre)GM24Gsat
Name: transgene insertion GM24, GENSAT Project at Rockefeller University
MGI ID: MGI:3836624
Synonyms: GM24, Tg(Chat-cre)24Gsat
Transgene: Tg(Chat-cre)GM24Gsat  Location: unknown  
Alliance: Tg(Chat-cre)GM24Gsat page
Transgene
origin
Strain of Origin:  FVB/N
Project Collection: GENSAT
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Chat-cre)GM24Gsat expression driven by 1 gene
 
Mutation details: A Cre-expression cassette, followed by a polyadenylation sequence to terminate transcription of the fusion transcript immediately after the recombinase gene, was inserted into a BAC vector at the initiating ATG codon in the first coding exon of the gene. The Cre expression pattern matches adult Chat gene expression (all cholinergic neurons) and is limited to motor neurons, with minimal expression in forebrain structures. (J:145110)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Chat (mouse)
Summary of all recombinase alleles driven by Chat.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:145110 Gong S, et al., Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci. 2007 Sep 12;27(37):9817-23
All:  37 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory