Tg(Pdx1-cre/Esr1*)1Mga Transgene Detail MGI Mouse (MGI:3839433)

Tg(Pdx1-cre/Esr1*)1Mga
Transgene Detail

Summary

Symbol:	Tg(Pdx1-cre/Esr1*)1Mga
Name:	transgene insertion 1, Maureen A Gannon
MGI ID:	MGI:3839433
Synonyms:	Pdx1^AI-III-Cre/ERT, pdx1^PBCreER^TM, Tg(Pdx1-cre/ERT)1Mga
Transgene:	Tg(Pdx1-cre/Esr1*)1Mga Location: unknown
Alliance:	Tg(Pdx1-cre/Esr1*)1Mga page

Transgene
origin

Strain of Origin:

Not Specified

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(Pdx1-cre/Esr1*)1Mga expression driven by 1 gene

Mutation details: The 1 kb islet enhancer was used to drive inducible islet-specific expression of a cre/Esr1 fusion. Three lines were created with line 1 exhibiting the strongest expression. (J:99581)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1. Comparative matrix view of recombinase activities

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pdx1-cre/Esr1*)1Mga

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:99581 Zhang H, et al., Efficient recombination in pancreatic islets by a tamoxifen-inducible Cre-recombinase. Genesis. 2005 Jul;42(3):210-7
All:	33 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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