Gene Expression Data
Assay Details
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Assay
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Reference:
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J:33496
Akhurst RJ, et al., TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development. 1990 Apr;108(4):645-56
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3839531
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Gene symbol:
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Tnr
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Gene name:
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tenascin R
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Antibody:
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anti-J1/tenascin
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
7.0 dpc:
embryonic day 7.0
(more  )
Specimen
7.0 dpc:
(close  )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 7.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS10: embryo mesoderm |
Weak |
Regionally restricted |
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Very weak expression in anterior mesoderm compared to posterior regions of the embryo.
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Specimen
5C:
embryonic day 9.5
(more )
Specimen
5C:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: heart atrium |
Absent |
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5C
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Authors report no expression seen during septation of the atria.
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| TS15: outflow tract |
Absent |
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5C
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Authors report no expression seen during septation of the atria.
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Specimen
5F:
embryonic day 9.5
(more )
Specimen
5F:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: endocardial cushion |
Present |
Regionally restricted |
5F
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Expression in the extracellular matrix surrounding mesenchymal cells of the cushion tissue.
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Specimen
5I:
embryonic day 9.5
(more )
Specimen
5I:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: endocardial cushion |
Present |
Regionally restricted |
5I
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Expression in the extracellular matrix surrounding mesenchymal cells of the cushion tissue.
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Specimen
5L:
embryonic day 10.5
(more )
Specimen
5L:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: heart |
Present |
Regionally restricted |
5L
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Expression in extracellular matrix surrounding mesenchymal cells. Authors report a correlation with regions of endothelium expressing Tgfb1 mRNA.
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Specimen
5O:
embryonic day 10.5
(more )
Specimen
5O:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: outflow tract |
Present |
Regionally restricted |
5O
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Expression in extracellular matrix surrounding mesenchymal cells. Authors report a correlation with regions of endothelium expressing Tgfb1 mRNA.
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| TS17: primitive ventricle |
Present |
Regionally restricted |
5O
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Expression in extracellular matrix surrounding mesenchymal cells. Authors report a correlation with regions of endothelium expressing Tgfb1 mRNA.
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Specimen
6B:
embryonic day 12.5
(more )
Specimen
6B:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: heart |
Present |
Regionally restricted |
6B
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Authors state that expression is most intense in atrioventricular valve mesenchyme immediately adjacent to endothelium expressing Tgfb1.
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Specimen
6E:
embryonic day 16.5
(more )
Specimen
6E:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: heart |
Present |
Regionally restricted |
6E
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Expression at the base of atrioventricular and pulmonary valve cusps.
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Specimen
at birth:
postnatal newborn
(more )
Specimen
at birth:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: heart valve |
Present |
Regionally restricted |
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Expression in a wide area at the base of the valves.
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Specimen
6G:
postnatal newborn
(more )
Specimen
6G:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
6H:
postnatal newborn
(more )
Specimen
6H:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: interatrial septum |
Present |
Regionally restricted |
6H
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Expression in the region of the foramen ovale.
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Specimen
6I:
postnatal day 8
(more )
Specimen
6I:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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postnatal day 8
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: atrioventricular valve |
Weak |
Regionally restricted |
6I
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Reduced expression in the region of the atrioventricular and semilunar valves.
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| TS28: semilunar valve |
Weak |
Regionally restricted |
6I
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Reduced expression in the region of the atrioventricular and semilunar valves.
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Specimen
6K:
postnatal adult
(more )
Specimen
6K:
(close )
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Genetic Background:
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involves: NIH * Parkes
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: aortic valve |
Weak |
Regionally restricted |
6K
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Weak expression limited to a small region at the base of the aortic valve.
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