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Sim1tm1.1(cre)Gld
Targeted Allele Detail
Summary
Symbol: Sim1tm1.1(cre)Gld
Name: single-minded family bHLH transcription factor 1; targeted mutation 1.1, Martyn Goulding
MGI ID: MGI:3839912
Synonyms: Sim1Cre
Gene: Sim1  Location: Chr10:50770850-50865248 bp, + strand  Genetic Position: Chr10, 24.87 cM, cytoband B3-B4
Alliance: Sim1tm1.1(cre)Gld page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147245
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Sim1tm1.1(cre)Gld expression driven by 1 gene
 
Mutation details: A cre gene followed by an frt flanked neo cassette were inserted via homologous recombination replacing the first exon. The neo cassette was then removed by Flp mediated recombination. At E11.5 Cre activity mirrors the pattern of endogenous Sim1 mRNA expression. (J:147245)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sim1 (mouse)
Summary of all recombinase alleles driven by Sim1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sim1 Mutation:  52 strains or lines available
References
Original:  J:147245 Zhang Y, et al., V3 spinal neurons establish a robust and balanced locomotor rhythm during walking. Neuron. 2008 Oct 9;60(1):84-96
All:  16 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory