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Tg(Prph1-cre)35Dmd
Transgene Detail
Summary
Symbol: Tg(Prph1-cre)35Dmd
Name: transgene insertion 35, David M Donovan
MGI ID: MGI:3841120
Synonyms: PCRE35, Per-cre
Transgene: Tg(Prph1-cre)35Dmd  Location: unknown  
Alliance: Tg(Prph1-cre)35Dmd page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Prph1-cre)35Dmd expression driven by 1 gene
 
Mutation detailsSequence encoding cre recombinase was adjoined to 5.8 kb of the peripherin 1 promoter region. In addition, a polyadenylation signal and peripherin 1 genomic sequence encompassing a portion of exon 1 through a portion of exon 3 was included downstream of cre. Transgenic expression was demonstrated in the dorsal root and trigeminal ganglia, the olfactory epithelium, and brainstem nuclei at E13. In addition, this is the only line reported for this construct that demonstrates sympathetic chain expression. (J:80936)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prph1 (species not specified)
Summary of all recombinase alleles driven by Prph1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:80936 Zhou L, et al., Murine peripherin gene sequences direct Cre recombinase expression to peripheral neurons in transgenic mice. FEBS Lett. 2002 Jul 17;523(1-3):68-72
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory