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Olig3tm1(cre)Ynka
Targeted Allele Detail
Summary
Symbol: Olig3tm1(cre)Ynka
Name: oligodendrocyte transcription factor 3; targeted mutation 1, Yasushi Nakagawa
MGI ID: MGI:3841452
Synonyms: OligCre
Gene: Olig3  Location: Chr10:19232287-19234352 bp, + strand  Genetic Position: Chr10, 8.33 cM
Alliance: Olig3tm1(cre)Ynka page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:147427
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Olig3tm1(cre)Ynka expression driven by 1 gene
 
Mutation details: was employed to replace the entire coding region of Olig3 was replaced via homologous recombination in ES cells using a targeting vector containing a cassette encoding Cre recombinase followed by a frt-Neo-frt (FNF) sequence. (J:147427)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Olig3 (mouse)
Summary of all recombinase alleles driven by Olig3.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Olig3 Mutation:  9 strains or lines available
References
Original:  J:147427 Vue TY, et al., Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97
All:  18 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory