About   Help   FAQ
Tg(SFTPC-cre)11Yo
Transgene Detail
Summary
Symbol: Tg(SFTPC-cre)11Yo
Name: transgene insertion 11, Yuichi Oike
MGI ID: MGI:3841690
Synonyms: SPC-Cre, SPCp-Cre, SPC-p Cre Tg
Transgene: Tg(SFTPC-cre)11Yo  Location: unknown  
Alliance: Tg(SFTPC-cre)11Yo page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(SFTPC-cre)11Yo expression driven by 1 gene
 
Mutation details: The transgenic construct contains the 4.1 kb human pro-surfactant protein C promoter (from an RPCl-11 human BAC clone) driving the Cre recombinase sequence. This construct was injected into the pronuclei of C57BL/6 blastocysts. Five founders were generated, and from crosses to transgenic reporter mice, lines 11 and 14 exhibited reporter expression in the lungs. Both lines contain a single transgene copy and were propagated for further study. (J:147388)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: SFTPC (human)
Summary of all recombinase alleles driven by SFTPC.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:147388 Hato T, et al., Angiopoietins contribute to lung development by regulating pulmonary vascular network formation. Biochem Biophys Res Commun. 2009 Apr 3;381(2):218-23
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory