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Tg(Cdh5-cre)1Nmoc
Transgene Detail
Summary
Symbol: Tg(Cdh5-cre)1Nmoc
Name: transgene insertion 1, Naoki Mochizuki
MGI ID: MGI:3842516
Synonyms: VE-cad-Cre
Transgene: Tg(Cdh5-cre)1Nmoc  Location: unknown  
Alliance: Tg(Cdh5-cre)1Nmoc page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Cdh5-cre)1Nmoc expression driven by 1 gene
 
Mutation details: A 2.5 kb fragment of the Cdh5 promoter region followed by the cre recombinase cDNA and the SV40 polyadenylation signal was inserted into the pBluescriptSKII plasmid. The transgene fragment was excised and microinjected into C57BL/6J fertilized oocytes. Three founder lines were obtained, All three showed no differences in reporter gene expression when crossed to EGFP or LacZ reporter mice. Line 1 with an estimated 2 copies of the Cdh5-cre transgene was analyzed further. (J:121366)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cdh5 (species not specified)
Summary of all recombinase alleles driven by Cdh5.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:121366 Kogata N, et al., Cardiac ischemia activates vascular endothelial cadherin promoter in both preexisting vascular cells and bone marrow cells involved in neovascularization. Circ Res. 2006 Apr 14;98(7):897-904
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory