Extl3<tm1Okam> Targeted Allele Detail MGI Mouse (MGI:3844733)

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Extl3^tm1Okam
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Extl3^tm1Okam
Name:	exostosin-like glycosyltransferase 3; targeted mutation 1, Hiroshi Okamoto
MGI ID:	MGI:3844733
Synonyms:	Extl3^flox
Gene:	Extl3 Location: Chr14:65289509-65387304 bp, - strand Genetic Position: Chr14, 33.86 cM, cytoband D1
Alliance:	Extl3^tm1Okam page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:148348
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 2 via homologous recombination. (J:148348)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Extl3 Mutation:	37 strains or lines available

References

Original:	J:148348 Takahashi I, et al., Important role of heparan sulfate in postnatal islet growth and insulin secretion. Biochem Biophys Res Commun. 2009 May 22;383(1):113-8
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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