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Tlx2tm1.1(cre)Rpk
Targeted Allele Detail
Summary
Symbol: Tlx2tm1.1(cre)Rpk
Name: T cell leukemia, homeobox 2; targeted mutation 1.1, Raj P Kapur
MGI ID: MGI:3846678
Synonyms: Hox11L1-Cre
Gene: Tlx2  Location: Chr6:83045306-83047206 bp, - strand  Genetic Position: Chr6, 35.94 cM, cytoband C3-D1
Alliance: Tlx2tm1.1(cre)Rpk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:148830
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Tlx2tm1.1(cre)Rpk expression driven by 1 gene
 
Mutation details: Part of exon 1 downstream of the translation initiation site was replaced with cre and a floxed neo cassette. The cre cassette was spontaneously excised. (J:148830)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tlx2 (mouse)
Summary of all recombinase alleles driven by Tlx2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tlx2 Mutation:  12 strains or lines available
References
Original:  J:148830 Kapur RP, et al., Hox11L1 expression by precursors of enteric smooth muscle: an alternative explanation for megacecum in HOX11L1-/- mice. Pediatr Dev Pathol. 2005 Mar-Apr;8(2):148-61
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory