Ern1 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:66969 Miyoshi K, et al., Characterization of mouse Ire1 alpha: cloning, mRNA localization in the brain and functional analysis in a neural cell line. Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):68-76
Assay type:	RNA in situ
MGI Accession ID:	MGI:3846682
Gene symbol:	Ern1
Gene name:	endoplasmic reticulum to nucleus signalling 1

Probe:	Ire1alpha cDNA
Probe preparation:	Antisense labelled with digoxigenin RNA

Results

Specimen 3A,B,C: postnatal week 8 (more

)
Note: (B,C) are high magnification views of the boxed areas in (A).

Structure	Level	Pattern	Image	Note
TS28: cerebral cortex	Present	Regionally restricted	3C , 3B , 3A	Expression is in neurons.
TS28: CA1 pyramidal cell layer	Present		3A , 3B , 3C
TS28: hippocampus CA2	Present	Regionally restricted	3C , 3B , 3A	Expression is in pyramidal cells.
TS28: hippocampus CA3	Present	Regionally restricted	3C , 3B , 3A	Expression is in pyramidal cells.
TS28: dentate gyrus granule cell layer	Present		3C , 3B , 3A

Specimen 3D,E: postnatal week 8 (more

)
Note: (E) is a high magnification view of the boxed area in (D).

Structure	Level	Pattern	Image	Note
TS28: main olfactory bulb granule cell layer	Weak		3D , 3E
TS28: main olfactory bulb mitral cell layer	Weak		3D , 3E

Specimen Not shown: postnatal week 8 (more

)

Structure	Level	Pattern	Image	Note
TS28: brainstem	Trace	Diffuse		Expression is in neurons, absent in oligodendrocytes and astrocytes.
TS28: cerebellum Purkinje cell layer	Trace	Diffuse		Expression is in neurons, absent in oligodendrocytes and astrocytes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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