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Tg(Atoh1-cre)1Mhos
Transgene Detail
Summary
Symbol: Tg(Atoh1-cre)1Mhos
Name: transgene insertion 1, Mikio Hoshino
MGI ID: MGI:3849083
Synonyms: Atoh1-Cre, Tg-Atoh1-Cre
Transgene: Tg(Atoh1-cre)1Mhos  Location: unknown  
Alliance: Tg(Atoh1-cre)1Mhos page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Atoh1-cre)1Mhos expression driven by 1 gene
 
Mutation detailsThe transgenic construct has a 1.6 kb PCR fragment containing the Atoh1 enhancer in the 3' UTR of the Atoh1 gene, followed by the cre recombinase cDNA with a metallothionein I polyadenylation signal. The purified construct was injected into fertilized oocytes. Nine founder lines were established and crossed to the R26R reporter line. Three lines recapitulated the endogenous Atoh1 expression profile and two lines were characterized further. (J:149533)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Atoh1 (species not specified)
Summary of all recombinase alleles driven by Atoh1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:149533 Fujiyama T, et al., Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development. 2009 Jun;136(12):2049-58
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory