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Tg(Cdkn1a-lacZ)44Wolf
Transgene Detail
Summary
Symbol: Tg(Cdkn1a-lacZ)44Wolf
Name: transgene insertion 44, C Roland Wolf
MGI ID: MGI:3850431
Synonyms: p21-LacZ
Transgene: Tg(Cdkn1a-lacZ)44Wolf  Location: unknown  
Alliance: Tg(Cdkn1a-lacZ)44Wolf page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe lacZ reporter was placed under the control of the Cdkn1a promoter. Seven of twelve founders passed the transgene on to the next generation. Three lines showed sufficiently high levels of lacZ expression for further study. Line 44 displays no basal lacZ expression but does show high levels of expression after etoposide treatment. (J:150334)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:150334 Vasey DB, et al., p21-LacZ reporter mice reflect p53-dependent toxic insult. Toxicol Appl Pharmacol. 2008 Mar 15;227(3):440-50
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory