About   Help   FAQ
Rhebtm1Pfw
Targeted Allele Detail
Summary
Symbol: Rhebtm1Pfw
Name: Ras homolog enriched in brain; targeted mutation 1, Paul Worley
MGI ID: MGI:3850507
Synonyms: Rheb1f, Rhebfl
Gene: Rheb  Location: Chr5:25007821-25047359 bp, - strand  Genetic Position: Chr5, 11.93 cM
Alliance: Rhebtm1Pfw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150108
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked PGK-neo cassette and second loxP site were inserted downstream of exon 3 via homologous recombination. (J:150108, J:168571)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rheb Mutation:  26 strains or lines available
References
Original:  J:150108 Delgoffe GM, et al., The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity. 2009 Jun 19;30(6):832-44
All:  28 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory