Tet2<Gt(AN0709)Wtsi> Gene trapped Allele Detail MGI Mouse (MGI:4345275)

Tet2^{Gt(AN0709)Wtsi}
Gene trapped Allele Detail

Summary

Symbol:	Tet2^{Gt(AN0709)Wtsi}
Name:	tet methylcytosine dioxygenase 2; gene trap AN0709, Wellcome Trust Sanger Institute
MGI ID:	MGI:4345275
Synonyms:	Tet2^LacZ
Gene:	Tet2 Location: Chr3:133169438-133250882 bp, - strand Genetic Position: Chr3, 61.84 cM
Alliance:	Tet2^{Gt(AN0709)Wtsi} page

Mutation
origin

Mutant Cell Line:	AN0709
Germline Transmission:	Earliest citation of germline transmission: J:174052
Parent Cell Line:	E14TG2a.4 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Sanger Inst. Gene Trap Res.

Mutation
description

Allele Type:

Gene trapped (Null/knockout, Reporter)

Mutation:

Insertion of gene trap vector Vector: pGT0lxr

Mutation details: The gene trap inserted between exon 9 and 10. Quantitative RT-PCR confirms transcript expression at 20% to 50% of wild-type lelves. This allele is hypomorphic. (J:174052)

Sequence Tags:

Sequence tag details (1 tag)

Genome Context:

Genome Browser view of this mutation

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Tet2 Mutation:	779 strains or lines available

References

Original:	J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24