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FuzGt(AN0439)Wtsi
Gene trapped Allele Detail
Summary
Symbol: FuzGt(AN0439)Wtsi
Name: fuzzy planar cell polarity protein; gene trap AN0439, Wellcome Trust Sanger Institute
MGI ID: MGI:4346364
Gene: Fuz  Location: Chr7:44545517-44552053 bp, + strand  Genetic Position: Chr7, 28.99 cM, cytoband B2
Alliance: FuzGt(AN0439)Wtsi page
Mutation
origin
Mutant Cell Line:  AN0439
Germline Transmission:  Earliest citation of germline transmission: J:154370
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsThe 5' end of the gene trap vector is inserted into intron 3, 28 bp upstream of the beginning of exon 4. In addition a large portion of the gene (intron 4 to exon 10) cannot be amplified in homozygous mice, indicating that the gene trap insertion is accompanied by an intragenic deletion spanning 7 exons. No beta-galactosidase activity is detected in homozygous or heterozygous embryos. (J:154370)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 59 assay results
In Structures Affected by this Mutation: 9 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fuz Mutation:  23 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory