Tg(Nes-cre/ERT2)7Vtlr
Transgene Detail
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| Symbol: |
Tg(Nes-cre/ERT2)7Vtlr |
| Name: |
transgene insertion 7, Verdon Taylor |
| MGI ID: |
MGI:4355234 |
| Synonyms: |
nestin::CreERT2 |
| Transgene: |
Tg(Nes-cre/ERT2)7Vtlr Location: unknown
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| Alliance: |
Tg(Nes-cre/ERT2)7Vtlr page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Nes-cre/ERT2)7Vtlr expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Homolog in Mouse |
Note |
| rat |
Nes (25491) |
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Mutation details: A CreERT2 cDNA was with a rabbit globin poly-adenylation sequence. The 2.5-kb fragment of the CreERT2-polyA was inserted downstream of the transcription initiation site of a 5.7 kb fragment of the rat nestin promoter and 5.4 kb of the fused rat nestin introns I/III. The linearized fragment was injected into the pronuclei of fertilized oocytes. 11 transgenic founders were identified with eight of the 11 lines that were established showed similar inducible recombination in the nervous system. Line 7 was analyzed further.
(J:151676)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Nes
(rat)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:151676 Giachino C, et al., Lineage analysis of quiescent regenerative stem cells in the adult brain by genetic labelling reveals spatially restricted neurogenic niches in the olfactory bulb. Eur J Neurosci. 2009 Jul;30(1):9-24 |
| All: |
3 reference(s) |
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Analysis Tools
