Tg(Prrx1-cre/ERT2,-EGFP)1Smkm
Transgene Detail
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| Symbol: |
Tg(Prrx1-cre/ERT2,-EGFP)1Smkm |
| Name: |
transgene insertion 1, Shunichi Murakami |
| MGI ID: |
MGI:4355342 |
| Synonyms: |
Prx1CreER-GFP |
| Transgene: |
Tg(Prrx1-cre/ERT2,-EGFP)1Smkm Location: unknown
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| Alliance: |
Tg(Prrx1-cre/ERT2,-EGFP)1Smkm page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Prrx1-cre/ERT2,-EGFP)1Smkm expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Prrx1 |
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Mutation details: The cre/ERT2 cDNA was cloned downstream of a 2.4 kb Prrx1 promoter. cDNA encoding an IRES-EGFP was inserted downstream of the cre/ERT2 sequence. This construct was injected into fertilized oocytes and 3 founders that expressed the transgene in the limbs were identified. Crosses to Rosa26-lacZ reporter mice identified two lines which had intense X-gal staining upon induction with tamoxifen. One line was chosen for further analysis.
(J:151681)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Prrx1
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:151681 Kawanami A, et al., Mice expressing GFP and CreER in osteochondro progenitor cells in the periosteum. Biochem Biophys Res Commun. 2009 Aug 28;386(3):477-82 |
| All: |
29 reference(s) |
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Analysis Tools
