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Tg(Dbh-icre)1Gsc
Transgene Detail
Summary
Symbol: Tg(Dbh-icre)1Gsc
Name: transgene insertion 1, Gunther Schutz
MGI ID: MGI:4355551
Synonyms: DBHCre, DBHiCre
Transgene: Tg(Dbh-icre)1Gsc  Location: unknown  
Alliance: Tg(Dbh-icre)1Gsc page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Dbh-icre)1Gsc expression driven by 1 gene
 
Mutation detailsUsing ET recombination, the coding sequence of iCre, followed by the bovine growth hormone polyadenylation signal, was introduced in-frame with the ATG of the Dbh gene in a PAC. The 150 kb transgenic construct was injected into he male pronuclei of fertilized C57BL/6 oocytes. (J:128636)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Dbh (species not specified)
Summary of all recombinase alleles driven by Dbh.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:128636 Stanke M, et al., Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling. Development. 2006 Jan;133(1):141-50
All:  50 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory