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Tg(Lhx6-icre)1Kess
Transgene Detail
Summary
Symbol: Tg(Lhx6-icre)1Kess
Name: transgene insertion 1, Nicoletta Kessaris
MGI ID: MGI:4355717
Synonyms: Lhx6-Cre, Lhx6Cre, Tg(Lhx6-cre)1Kess
Transgene: Tg(Lhx6-icre)1Kess  Location: unknown  
Alliance: Tg(Lhx6-icre)1Kess page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Lhx6-icre)1Kess expression driven by 1 gene
 
Mutation details: Homologous recombination in bacteria was used to modify a 235Kb BAC RP24-384G1 containing 137 Kb upstream and 80 Kb downstream of the Lhx6 gene. An icre (improved cre) coding sequence was fused to the ATG of Lhx6 in exon 1 using a PCR-based approach. An SV40 polyA was inserted downstream of iCre. The construct was designed to delete the coding sequence of exon 1, as well as the first 80 bp from the first intron. Mice were generated by pronuclear injection of the construct into fertilized oocytes. No line number is given. (J:154447)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Lhx6 (mouse)
Summary of all recombinase alleles driven by Lhx6.
 

Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:125700 Fogarty M, et al., Spatial genetic patterning of the embryonic neuroepithelium generates GABAergic interneuron diversity in the adult cortex. J Neurosci. 2007 Oct 10;27(41):10935-46
All:  55 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory