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Tg(Ppp1r1b-cre)1Meeh
Transgene Detail
Summary
Symbol: Tg(Ppp1r1b-cre)1Meeh
Name: transgene insertion 1, Michelle E Ehrlich
MGI ID: MGI:4356000
Synonyms: A11K20IRESCre, D32-Cre, D9-Cre, DARPP-32Cre
Transgene: Tg(Ppp1r1b-cre)1Meeh  Location: unknown  
Alliance: Tg(Ppp1r1b-cre)1Meeh page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Ppp1r1b-cre)1Meeh expression driven by 1 gene
 
Mutation details: An IRES-cre fragment with a nuclear localization signal sequence (nls) and an SV40 polyA sequence was inserted into a plasmid containing genomic fragments of Ppp1rb1 from 3 clones. The transgenic construct was injected into fertilized C57BL/6 oocytes. Two potential founders were obtained but only one founder was successfully bred to generate the line. Insertion of a single copy of the transgene was verified by Southern blot. (J:127863)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Ppp1r1b (species not specified)
Summary of all recombinase alleles driven by Ppp1r1b.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:127863 Bogush AI, et al., DARPP-32 genomic fragments drive Cre expression in postnatal striatum. Genesis. 2005 May;42(1):37-46
All:  11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory