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Gene Expression Data
Assay Details
Assay
Reference: J:76619 Barlow GM, et al., Mammalian DSCAMs: roles in the development of the spinal cord, cortex, and cerebellum?. Biochem Biophys Res Commun. 2002 May 10;293(3):881-91
Assay type: RNA in situ
MGI Accession ID: MGI:4356124
Gene symbol: Dscaml1
Gene name: DS cell adhesion molecule like 1
Probe: DSCAML1 probe2
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2Ab: embryonic day 12.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS20: spinal cord Present Graded 2Ab Dorsal expression predominates.

Specimen 2Bg: embryonic day 12.5 (more )
Note: This is a transverse section at the level of the heart and forelimbs.
Structure Level Pattern Image Note
TS20: spinal cord Present Graded 2Bg Dorsal expression predominates along the rostro-caudal axis of the spinal cord.

Specimen 2Bl: embryonic day 12.5 (more )
Note: This is a transverse section at the level of the liver and hindlimbs.
Structure Level Pattern Image Note
TS20: spinal cord Present Graded 2Bl Dorsal expression predominates along the rostro-caudal axis of the spinal cord.

Specimen 3b: embryonic day 10.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS17: future spinal cord Absent 3b

Specimen 3d: embryonic day 11.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 3d Expression is present in two distinct bands. It is present in the neuroepithelial cells of the dorsal neural tube, cells which will migrate to form the dorsal horns, the spinocerebral tract, and the autonomic system.

Specimen 3f: embryonic day 12.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS20: spinal cord Present Graded 3f Expression in the dorsal sensory cells predominates.

Specimen Not shown: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: spinal cord Present Graded Expression in the dorsal sensory cells predominates.

Specimen 3h: embryonic day 18.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS26: spinal cord Present Uniform 3h Expression is present throughout the spinal cord, with no distinct ventral/dorsal gradient.

Specimen 3j: postnatal adult (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS28: spinal cord Trace 3j Expression is barely detectable above background.

Specimen Not shown: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Strong Regionally restricted Expression is present in the preplate plexus, particularly in the Cajal-Retzius cells.
TS19: telencephalon ventricular layer Present

Specimen 4b: embryonic day 12.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS20: cerebral cortex Strong Regionally restricted 4b Expression is present in the outermost layer of the neocortex, with strong expression in the region of the future olfactory lobe, where the neopallial cortex overlies the olfactory epithelium.
TS20: ganglionic eminence Present Non-Uniform 4b Expression is stronger dorsally.
TS20: midbrain Present 4b
TS20: thalamus Present 4b
TS20: medulla oblongata Present Non-Uniform 4b Expression is stronger dorsally.
TS20: metencephalon Present Non-Uniform 4b Expression is stronger dorsally.
TS20: cerebellum primordium Present 4b Expression is present in the rhombic lip of His.

Specimen 4d: embryonic day 14.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted 4d Expression is present in two distinct bands.
TS22: ganglionic eminence Present 4d
TS22: medulla oblongata Present 4d
TS22: midbrain Present 4d
TS22: spinal cord Present 4d
TS22: tectum Present 4d

Specimen 4f: postnatal day 1 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS27: neocortex layer Present Non-Uniform 4f Expression is present in all layers.
TS27: cortical layer II Present 4f This is the layer with the strongest expression level.

Specimen 4h: postnatal day 1 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS27: neocortex layer Present Non-Uniform 4h Expression is present in all layers.
TS27: cortical layer II Present 4h This is the layer with the strongest expression level.

Specimen 5b: postnatal month 6 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: cortical layer II Present 5d , 5b The strongest cortical expression level is found in the granule cells of layer 2.
TS28: hippocampus Present Non-Uniform 5d , 5b
TS28: dentate gyrus granule cell layer Present 5b , 5d This is one of the regions of strongest expression in the hippocampus.
TS28: hippocampus pyramidal cell layer Present 5b , 5d This is one of the regions of strongest expression in the hippocampus.

Specimen 5f: postnatal day 7 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: main olfactory bulb Strong Regionally restricted 5f There is strong expression in the neuronal layers.

Specimen 6b: postnatal newborn (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS27: cerebellum Present Non-Uniform 6b Structural definition is not yet distinct.
TS27: cerebellum external granule cell layer Present 6b

Specimen 6d: postnatal adult (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 6d , 6f
TS28: cerebellum granule cell layer Strong 6d , 6f


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory