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Ipwtm1Jbro
Targeted Allele Detail
Summary
Symbol: Ipwtm1Jbro
Name: imprinted gene in the Prader-Willi syndrome region; targeted mutation 1, Jurgen Brosius
MGI ID: MGI:4356427
Gene: Ipw  Location: Chr7:59268906-59328626 bp, - strand  Genetic Position: Chr7, 34.0 cM
Mutation
origin
Germline Transmission:  Unknown
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Not Specified)
Mutation:    Insertion
 
Mutation details: A cassette containing a puromycin resistance gene, a loxP site, and the 3' half of the HPRT mini-gene, was inserted 3' of Ipw. (J:152022)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ipw Mutation:  0 strains or lines available
Notes
Cre mediated recombination of this allele in combination with Snord116tm1Jbro yields Del(7Ipw-Snord116)1Jbro.
References
Original:  J:152022 Skryabin BV, et al., Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation. PLoS Genet. 2007 Dec 28;3(12):e235
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory