Tg(KRT14-cre/Esr1*)3Brst
Transgene Detail
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| Symbol: |
Tg(KRT14-cre/Esr1*)3Brst |
| Name: |
transgene insertion 3, Barry R Stripp |
| MGI ID: |
MGI:4357971 |
| Synonyms: |
K14-CreERt |
| Transgene: |
Tg(KRT14-cre/Esr1*)3Brst Location: unknown
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| Alliance: |
Tg(KRT14-cre/Esr1*)3Brst page
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(KRT14-cre/Esr1*)3Brst expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
KRT14 |
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Mutation details: The transgenic construct contains the KRT14 promoter/enhancer followed by the cre recombinase cDNA fused to the sequence of an altered hormone-binding domain of the mouse estrogen receptor (cre/Ert). The transgene also contains a rabbit beta-globin 5' UTR region and intronic sequence 5' to the cre cDNA, as well as the KRT14 3' UTR and polyadenylation site 3' to the cre sequence. The construct was injected into FVB/N zygotes. Three founders were identified.
(J:150033)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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KRT14
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:150033 Hong KU, et al., Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium. Am J Pathol. 2004 Feb;164(2):577-88 |
| All: |
8 reference(s) |
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Analysis Tools
