Foxd1<tm1(GFP/cre)Amc> Targeted Allele Detail MGI Mouse (MGI:4359653)

Foxd1^{tm1(GFP/cre)Amc}
Targeted Allele Detail

Summary

Symbol:	Foxd1^{tm1(GFP/cre)Amc}
Name:	forkhead box D1; targeted mutation 1, Andrew P McMahon
MGI ID:	MGI:4359653
Synonyms:	FoxD1-cre, Foxd1EGFPcre, Foxd1^GC, FoxD1-GC, Foxd1GC, Foxd1-GFP-Cre
Gene:	Foxd1 Location: Chr13:98490753-98493213 bp, + strand Genetic Position: Chr13, 51.96 cM
Alliance:	Foxd1^{tm1(GFP/cre)Amc} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:148456
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Mutation
description

Allele Type:

Targeted (Recombinase)

Mutation:

Insertion

Foxd1^{tm1(GFP/cre)Amc} expression driven by 1 gene

Mutation details: A targeting vector was designed to insert an eGFP/cre (GC) fusion protein coding sequence and frt-flanked PGK-neob-pA selection cassette into the 5' untranslated region of the Forkhead box D1 (Foxd1) targeted gene. (J:158051)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxd1 (mouse) Summary of all recombinase alleles driven by Foxd1. Comparative matrix view of recombinase activities Alliance mouse Foxd1 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

138 assay results
9 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Foxd1 Mutation:	13 strains or lines available

References

Original:	J:148456 Humphreys BD, et al., Intrinsic epithelial cells repair the kidney after injury. Cell Stem Cell. 2008 Mar 6;2(3):284-91
All:	84 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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