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Wnt4tm3(EGFP/cre)Amc
Targeted Allele Detail
Summary
Symbol: Wnt4tm3(EGFP/cre)Amc
Name: wingless-type MMTV integration site family, member 4; targeted mutation 3, Andrew P McMahon
MGI ID: MGI:4359657
Synonyms: Wnt4GC
Gene: Wnt4  Location: Chr4:137004946-137026812 bp, + strand  Genetic Position: Chr4, 69.8 cM
Alliance: Wnt4tm3(EGFP/cre)Amc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152419
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Wnt4tm3(EGFP/cre)Amc expression driven by 1 gene
 
Mutation details: The targeting vector was designed to insert an eGFP/cre (GC) fusion protein coding sequence and an Frt-flanked PGK-neo-polyA selection cassette into the initiation codon of the Wnt4 gene. (J:192186)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Wnt4 (mouse)
Summary of all recombinase alleles driven by Wnt4.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 8 assay results
1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt4 Mutation:  21 strains or lines available
References
Original:  J:152419 Mugford JW, et al., High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population. Dev Biol. 2009 Sep 15;333(2):312-23
All:  11 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory