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Mir208atm1Dzw
Targeted Allele Detail
Summary
Symbol: Mir208atm1Dzw
Name: microRNA 208a; targeted mutation 1, Da-Zhi Wang
MGI ID: MGI:4359821
Gene: Mir208a  Location: Chr14:55186517-55186599 bp, - strand  Genetic Position: Chr14, 28.0 cM
Alliance: Mir208atm1Dzw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152696
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA DNA fragment from intron 31 of the Myh6 gene containing the micro RNA coding sequence was replaced with a floxed neo cassette via homologous recombination. (J:152696)
Generation of the Mir208atm1Dzw and Mir208atm1.1Dzw alleles
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir208a Mutation:  2 strains or lines available
References
Original:  J:152696 Callis TE, et al., MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory