Tg(Pcp2-cre/ERT2,-ALPP)1Alj
Transgene Detail
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Symbol: |
Tg(Pcp2-cre/ERT2,-ALPP)1Alj |
Name: |
transgene insertion 1, Alexandra L Joyner |
MGI ID: |
MGI:4360711 |
Synonyms: |
Pcp2-CreER-IRES-hAP |
Transgene: |
Tg(Pcp2-cre/ERT2,-ALPP)1Alj Location: unknown
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Alliance: |
Tg(Pcp2-cre/ERT2,-ALPP)1Alj page
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Transgene Type: |
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Transgenic (Inducible, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Pcp2-cre/ERT2,-ALPP)1Alj expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Pcp2 |
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Mutation details: A 3kb genomic fragment containing a truncated Pcp2 enhancer and gene drives cre/ERT2 followed by an IRES-ALPP (human placental alkaline phosphatase) sequence. The construct was injected into FVB/N oocytes and four founders were obtained. The line displaying the strongest expression in embryonic Purkinje cell (PC) clusters and adult medial-lateral PC stripes was chosen for further analysis.
(J:152951)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pcp2
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:152951 Sillitoe RV, et al., Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections. Neuroscience. 2009 Sep 1;162(3):574-88 |
All: |
1 reference(s) |
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