Fabp7<tm2(cre/PGR*)Ksak> Targeted Allele Detail MGI Mouse (MGI:4360725)

Fabp7^{tm2(cre/PGR*)Ksak}
Targeted Allele Detail

Summary

Symbol:	Fabp7^{tm2(cre/PGR*)Ksak}
Name:	fatty acid binding protein 7, brain; targeted mutation 2, Kenji Sakimura
MGI ID:	MGI:4360725
Synonyms:	BFABP-CrePR, Fabp7^{tm1(crePR)Ksak}, Fabp7^{tm2(cre/PGR)Ksak}
Gene:	Fabp7 Location: Chr10:57661019-57664546 bp, + strand Genetic Position: Chr10, 29.25 cM
Alliance:	Fabp7^{tm2(cre/PGR*)Ksak} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:104881
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:

Targeted (Inducible, Recombinase)

Inducer:

mifepristone

Mutation:

Insertion

Fabp7^{tm2(cre/PGR*)Ksak} expression driven by 1 gene

Mutation details: The endogenous gene's promoter drives expression of a DNA sequence encoding a fusion protein in which Cre recombinase is joined to the ligand binding domain (LBD) of the human progesterone receptor lacking the carboxyl terminal 42 amino acids. The chimeric recombinase protein is not constitutively active; its activity is inducible by binding of the synthetic progesterone analog RU486 to the truncated progesterone LBD. (J:104881, J:122587)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Fabp7 (mouse) Summary of all recombinase alleles driven by Fabp7. Alliance mouse Fabp7 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Fabp7 Mutation:	18 strains or lines available

References

Original:	J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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