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Peli1tm1Tigm
Targeted Allele Detail
Summary
Symbol: Peli1tm1Tigm
Name: pellino 1; targeted mutation 1, Texas A&M Institute for Genomic Medicine
MGI ID: MGI:4361448
Gene: Peli1  Location: Chr11:21041291-21100323 bp, + strand  Genetic Position: Chr11, 13.81 cM, cytoband A3.2
Alliance: Peli1tm1Tigm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152781
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exons 1 and 2 were replaced with a lacZ/neo cassette. The absence of full-length transcript expression was confirmed by RT-PCR. (J:152781)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Peli1 Mutation:  31 strains or lines available
References
Original:  J:152781 Chang M, et al., Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Nat Immunol. 2009 Oct;10(10):1089-95
All:  12 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory