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Tg(Des-cre)1Zli
Transgene Detail
Summary
Symbol: Tg(Des-cre)1Zli
Name: transgene insertion 1, Zhenlin Li
MGI ID: MGI:4362109
Synonyms: Des-Cre
Transgene: Tg(Des-cre)1Zli  Location: unknown  
Alliance: Tg(Des-cre)1Zli page
Transgene
origin
Strain of Origin:  C57BL/6 or DBA/2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Des-cre)1Zli expression driven by 1 gene
 
Mutation detailsThis transgene contains 4.6 kb of DNA from the mouse desmin gene (nucleotides -4005 to +608), including 5' regulatory sequences, the 5' untranslated region (UTR) and exon 1 through nucleotide +608, driving expression of Cre recombinase with a nuclear localization signal. This promoter has been shown to direct expression in the heart from embryonic day (E) 7.5 and in skeletal muscle and some vascular smooth muscle cells from E9.5. (J:65247, J:82809)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Des (mouse)
Summary of all recombinase alleles driven by Des.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
According to Zhenlin Li, donor of mice bearing this transgene to the European Mouse Mutant Archive (EMMA), it was generated in a "C57BL6/DBA2" genetic background.
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory