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Tg(Tagln-cre)1Zli
Transgene Detail
Summary
Symbol: Tg(Tagln-cre)1Zli
Name: transgene insertion 1, Zhenlin Li
MGI ID: MGI:4365411
Synonyms: SM22-Cre
Transgene: Tg(Tagln-cre)1Zli  Location: unknown  
Alliance: Tg(Tagln-cre)1Zli page
Transgene
origin
Strain of Origin:  C57BL/6 or DBA/2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Tagln-cre)1Zli expression driven by 1 gene
 
Mutation details: Expression of nuclear-localized Cre recombinase is driven by the promoter region of the mouse tagln gene, including 2126 bp of 5' flanking sequence, the first exon, the first intron and the first 15 bp of the second intron with the last four nucleotides modified from CATG to GCTT to remove the initiation codon. In transgenic mice, Cre is expressed initially in the heart and somites and later in the arteries of the vascular system, but not in the visceral muscles nor in the veins. (J:34770, J:82809)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tagln (mouse)
Summary of all recombinase alleles driven by Tagln.
 

Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
According to Zhenlin Li, donor of mice bearing this transgene to the European Mouse Mutant Archive (EMMA), it was generated in a "C57BL6/DBA2" genetic background.
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory