Gene Expression Data
Assay Details
Assay
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Reference:
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J:151330
Bai XH, et al., ADAMTS-7, a direct target of PTHrP, adversely regulates endochondral bone growth by associating with and inactivating GEP growth factor. Mol Cell Biol. 2009 Aug;29(15):4201-19
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:4365941
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Gene symbol:
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Adamts7
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Gene name:
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ADAM metallopeptidase with thrombospondin type 1 motif 7
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Antibody:
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anti-ADAMTS-7
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Detection system:
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Secondary antibody coupled to alkaline phosphatase
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Results
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Specimen
1Ca:
embryonic day 11.5
(more )
Specimen
1Ca:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 11.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS19: embryo mesenchyme |
Present |
Regionally restricted |
1Ca
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Expression in proliferating mesenchymal cells.
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Specimen
1Cb:
embryonic day 13.5
(more )
Specimen
1Cb:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS21: pre-cartilage condensation |
Present |
Regionally restricted |
1Cb
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Expression clearly detectable in the center of a mesenchymal condensation and around it
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Specimen
1Cc:
embryonic day 15.5
(more )
Specimen
1Cc:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS23: cartilage |
Strong |
Regionally restricted |
1Cc
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Prominent expression in proliferating and prehypertrophic chondrocytes.
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Specimen
1Cd:
embryonic day 17.5
(more )
Specimen
1Cd:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 17.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
|
Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS25: cartilage |
Present |
Regionally restricted |
1Cd
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Expression in proliferating and prehypertrophic chondrocytes in growth plates.
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Specimen
1Ce:
postnatal newborn
(more )
Specimen
1Ce:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS27: epiphyseal plate |
Present |
Regionally restricted |
1Ce
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Expression in proliferating and prehypertrophic chondrocytes in growth plates.
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Specimen
1Cf:
postnatal day 21
(more )
Specimen
1Cf:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 21
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS28: epiphyseal plate |
Present |
Regionally restricted |
1Cf
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Expression throughout growth plate chondrocytes.
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Specimen
7Cb/c:
embryonic day 18.5
(more )
Specimen
7Cb/c:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS26: bone |
Present |
Regionally restricted |
7Cc
,
7Cb
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Expression in growth plate chondrocytes.
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Specimen
7Ce/f:
(close )
Genetic Background:
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involves: 129S2/SvPas
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Mutant Allele(s):
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Pthlhtm1Hmk/Pthlhtm1Hmk
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Age:
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embryonic day 18.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Structure |
Level |
Pattern |
Image |
Note |
TS26: bone |
Weak |
Regionally restricted |
7Cf
,
7Ce
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Expression in growth plate chondrocytes markedly reduced compared with wild type.
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