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Prdm1tm1.1Liz
Targeted Allele Detail
Summary
Symbol: Prdm1tm1.1Liz
Name: PR domain containing 1, with ZNF domain; targeted mutation 1.1, Elizabeth K Bikoff
MGI ID: MGI:4366868
Synonyms: Prdm1deltaex1A
Gene: Prdm1  Location: Chr10:44313173-44404497 bp, - strand  Genetic Position: Chr10, 23.24 cM
Alliance: Prdm1tm1.1Liz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153979
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 1A was replaced with a floxed neo cassette. Transient cre expression in ES cells removed the neo cassette. (J:153979)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Prdm1 Mutation:  66 strains or lines available
References
Original:  J:153979 Morgan MA, et al., Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. Mol Cell Biol. 2009 Nov;29(21):5813-27
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory